Abstract:【Objective】 To compare the therapeutic effects of microendoscopic discectomy and open surgery for lumbar body posterior bony edges separation. 【Methods】 31 cases of lumbar body posterior bony edges separation undergone surgical treatment from October 2009 to April 2012 were reviewed retrospectively. 14 of 31 operated accurately were reduced pressure by microendoscopic surgery (minimally invasive group), the other cases were operated open surgery (open group).The operation time, intraoperative blood loss, seroma volume of drainage after surgery, length of hospital stay, and preoperative and postoperative VAS score, JOA score, ODI evaluation, were evaluated during the follow-up. 【Results】 All patients were followed up for 12 to 28 months, average (16.8±2.4) months. The operation time, intraoperative blood loss, seroma volume of drainage after surgery and length of hospital stay in minimally invasive group were significantly less than the open group (P <0.05). The postoperation 3 months, the last follow-up pain VAS scores, JOA score, ODI score in two groups were compared with preoperative with significant difference (P <0.05), postoperative 3 months, the last follow-up pain VAS score, JOA score, there was no statistically significant difference of ODI score between the two groups (P <0.05). At the time of the last follow-up modified Macnab criteria was used to evaluate the clinical effect, the open group was 94.1%, the minimally invasive group was 92.9%. 【Conclusion】 Microendoscopic and open surgery treatment of treatment for lumbar body posterior bony edges separation can obtain satisfactory therapeutic effects, minimally invasive surgery advantage in the early days, there was no difference in the mid-term therapeutic effects.