Abstract:【Objective】 To assess the effectiveness of the intraoperative ultrasound and choledochoscope which were applied in the surgical treatment of hepatolithiasis. 【Methods】 The outcomes of 44 cases with hepatolithiasis who were treated by the intraoperative ultrasound and choledochoscope in the operation were retrospectively analyzed. 【Results】 The complications of bile leak, abdominal hemorrhage and hepatic failure didn't occurred postoperation. No death occurred. T-tube cholangiography and B ultrasound were performed after 8 weeks. 2 cases had occurred residual calculus. These cases were treated by the choledochoscope and the residual calculus were extracted by the basket. 【Conclusion】 The blindness of the traditional surgical treatment as the lithotomy could be reduced by applying the intraoperative ultrasound and choledochoscope in the operation. The occurrence of residual biliary calculus would be decreased significantly, and the value of this surgical technology would become important in the clinical treatment.