耻骨上膀胱造瘘四分区前列腺剜切术的临床疗效研究

Clinical efficacy of four quadrants enucleation of prostate over pubis with cystostomy and traditional enucleation

摘要:

目的 耻骨上膀胱造瘘四分区前列腺剜切术治疗良性前列腺增生的疗效和安全性。方法 2011年6月～2013年6月，对212例BPH患者分组，实验组119例，对照组93例，实验组行耻骨上造瘘四分区前列腺剜切术；对照组行传统前列腺剜切术。观察两组术中出血量、手术时间、导尿管留置时间、术后住院时间、冲洗时间、冲洗液量及住院费用，观察两组患者术后6个月IPSS、QOL、Qmax(mL/s)和PVR(mL)，以及术后6个月尿道狭窄和尿失禁并发症。结果 观察两组术中出血量、手术时间、导尿管留置时间、术后住院时间、冲洗时间、冲洗液量及住院费用，实验组均优于对照组，差异有显著性，P <0.05；观察两组患者术后6个月IPSS、QOL、Qmax(mL/s)和PVR(mL)，差异无显著性，P >0.05；观察组与实验组术后6个月尿道狭窄和尿失禁发生率比较差异无显著性(P >0.05)。结论 耻骨上膀胱造瘘四分区前列腺剜切术疗效确切，手术时间可控，安全性较高，值得推广。

Abstract:

【Objective】 To investigate the clinical effect and safety of four quadrants enucleation of prostate over pubis with cystostomy in the treatment of benign prostatic hyperplasia (BPH). 【Methods】 From June 2011 to June 2013, 212 BPH patients were divided into test group(119 patients), treated with four quadrants enucleation of prostate over pubis with cystostomy and control group (93 patients), treated with conventional enucleation of prostate. The time of operation, blood loss in operation, catheter indwelling time, days in hospital after operation, washing time, washing fluid amount, hospitalization expenses and situation of IPSS, QOL, Qmax (mL/s), PVR (mL) and urethrostenosis, urinary incontinence complications in 6 months' follow-up were compared between the two groups. 【Results】 By comparison, the time of operation, blood loss in operation, catheter indwelling time, days in hospital after operation, washing time, washing fluid amount and hospitalization expenses in the test group were better than the control group. The difference was statistically significant (P<0.05); The situation of IPSS, QOL, Qmax (mL/s), PVR(mL) of the two groups in 6 months' follow-up had no statistically significant difference (P>0.05); The occurrence rate of urethrostenosis, urinary incontinence complications in two groups in 6 months' follow-up, the difference was not statistically significant (P>0.05). 【Conclusion】 Four quadrants enucleation of prostate over pubis with cystostomy is safe, effective, time controllable and clinical applicable.