神经内镜辅助下治疗室管膜下巨细胞星形细胞瘤

Neuroendoscopic-assisted therapy for the subependymal giant cell astrocytoma

摘要:

目的 探讨神经内镜辅助下手术治疗室管膜下巨细胞星形细胞瘤(SEGA) 的临床疗效。 方法 2009年6月～2012年12月，共7例室管膜下巨细胞星形细胞瘤患者均合并脑积水，在神经内镜辅助下行7例手术，其中额部开颅经胼胝体入路切除肿瘤5例，均为全切除；额部开颅经侧脑室前角切除肿瘤2例，均为全切除；同时行三脑室底造瘘解除脑积水。患者均得到随访，随访时间12～30个月。 结果 7例患者肿瘤均为全切除，随访至今无患者死亡，无肿瘤复发，无手术相关的并发症。 结论 神经内镜辅助下手术治疗SEGA能减少脑组织创伤，同时解除脑积水，具有较好的临床疗效。

Abstract:

【Objective】 To investigate the clinical efficacy of neuroendoscopic-assisted surgery for subependymal giant cell astrocytoma (SEGA) . 【Methods】 From June 2009 to December 2012, a total of 7 cases of subependymal giant cell astrocytoma associated with hydrocephalus were removed by neuroendoscopic-assisted surgery, 5 tumors were surgically resected through transcallosal approach, 2 through frontal transcortical approach and three-ventriculostomy relieve hydrocephalus simultaneously. Follwoing-up ranged from 12 to 30 months. 【Results】 7 patients were tumor resection, the patient follow-up has no death,no tumor recurrence, no surgery-related complications. 【Conclusion】 Neuroendoscopic-assisted surgery can reduce brain trauma and relieve hydrocephalus, has a better clinical efficacy.