Abstract:【Objective】 To study gastroscopic characteristics of children with upper digestive tract symptoms and assess the clinical application value of gastroscopy in the diagnosis of children among different age groups. 【Methods】 The data of gastroscopic examination in children with upper digestive tract symptoms among different age groups were analyzed retrospectively. The patients were divided into four groups by age ranges including infancy (<3 ages), preschool age (3 ages to 6 ages), school age (6 ages to 11 ages), adolescence (12 ages to 14 ages). The differences in children with upper digestive tract symptoms among different age groups in terms of gastroscopic characteristics were compared. 【Results】 ①1 726 patients had accepted gastroscopy 1 805 times, including infancy 205 cases, preschool age 556 cases, school age 783 cases, adolescence 182 cases. ②Chronic gastritis was the common causes in children with upper gastrointestinal tract symptoms. The most frequent findings were the digestive tract malformation and upper digestive tract foreign bodies in infancy. Henoch-Schonlein purpura and esophageal varices occurred mostly in preschool age and school age. The proportion of peptic ulcer in school age and adolescence was significantly higher than other group (P <0.005). ③The proportion of peptic ulcer in children was 11.4% (197/1 726). Among them, the proportion of duodenal ulcer in children was 86.3% (170/197), gastric ulcer 10.2% (20/197), complex ulcer 3.6% (7/197). ④The location of the gastritis erosive was different in children with upper digestive tract symptoms among different age groups. The proportion of stomach fundus was the highest in gastritis erosive over the age of 3 years. The predisposed location of duodenal ulcer was most in the anterior wall. 【Conclusion】The most common cause is different in children with upper digestive tract symptoms. Gastroscopy examination is the main method of diagnosis of upper digestive tract symptoms among different age groups. This shows diagnosis value in children with upper disease tract symptoms.