【Objective】 To investigate the feasibility of transumbilical single-port laparoscopic cholecystectomy (TUSPLC) by general instruments and how to make the simple device. 【Methods】 The clinical date of 128 patients undergoing TUSPLC by ordinary equipment from June 2012 to October 2013 in our hospital were retrospectively analyzed. 【Results】 Only one case was converted to three-port laparoscopic cholecystectomy because of Mirizzi Syndrome. Other 127 cases were performed transumbilical single-port laparoscopic cholecystectomy by general instruments successfully. No post-operative complications were observed after a 1-16 months follow-up. 【Conclusion】 Transumbilical single-port laparoscopic cholecystectomy using the simple device by general instruments is safe, effective and reliable. This operation can indeed achieve a more minimally invasive and excellent cosmetic results. It can be performed without specialized instruments and at no extra cost, so it is worth being popularized in primary hospitals.