窄带显像膀胱镜引导下经尿道膀胱肿瘤电切术降低膀胱肿瘤术后复发率

Narrow-band imaging guided transurethral resection of bladder cancer can decrease local recurrence comparing to white light guided resection

摘要:

目的 探讨窄带现象膀胱镜降低非肌层浸润性膀胱肿瘤行经尿道等离子电切术后复发率的作用。 方法 非肌层浸润性膀胱肿瘤患者184例，105例接受普通白光引导下的经尿道等离子电切术，79例接受窄带显像膀胱镜引导下的经尿道等离子电切术。比较两者的无复发生存率、住院时间、手术时间及并发症等相关指标。 结果 所有患者均安全完成手术。两组在平均手术时间、平均尿管留置时间、平均住院时间及并发症率方面差异无显著性。术后随访8～64个月。普通白光引导下的经尿道等离子电切术组有38例出现复发，窄带显像膀胱镜引导下的经尿道等离子电切术组有9例出现复发。生存分析提示两组在无复发生出率上差异有显著性（P =0.000）。 结论 窄带显像膀胱镜引导下的经尿道等离子电切术是一种安全、可行的治疗非肌层浸润性膀胱肿瘤的术式。窄带显像膀胱镜引导下的经尿道等离子电切术可降低短期内膀胱肿瘤复发率。

Abstract:

【Objective】 To investigate the roll of narrow-band imaging guided transurethral resection in decreasing the recurrence of none-muscle invasive bladder cancer comparing to white light guided transurethral resection. 【Methods】 184 none-muscle invasive bladder cancer patients were divided into two groups: 105 in white light guided transurethral resection group and 79 in narrow-band imaging guided transurethral resection group. The recurrent-free survival ratio, hospital day, complication rate were compared between two groups. 【Results】 All patients received operation safely. No difference could be found between two groups in recurrent-free ratio, hospital day, complication rate. The follow up were from 8 months up to 64 months. 38 patients recurrenced in white light guided transurethral resection group while only 9 patients recruuented in narrow-band imaging guided transurethral resection group. 【Conclusion】 Narrow-band imaging guided transurethral resection is a safe, fessible method to treat none-muscle invasive bladder cancer. Narrow-band imaging guided transurethral resection can decrease the local recurrence comparing to white light guided transurethral resection.