输尿管封堵器联合气压弹道碎石治疗输尿管结石的临床研究

Clinical study of occluder combined pneumatic lithotripsy in the treatment of ureteral calculi

摘要:

目的 探讨输尿管封堵器联合气压弹道碎石在输尿管结石治疗中的临床疗效。方法 将该院收治的78例输尿管结石患者随机分为观察组40例和对照组38例，对照组采用气压弹道碎石术，观察组采用输尿管封堵器联合气压弹道碎石术。对比两组患者手术疗效、手术时间、住院时间、血尿时间以及治疗后BUN、Cr水平变化和两组患者不良反应发生情况。结果 两组一次性碎石率比较χ2=5.5038（P =0.0190）；两组1个月结石排净率比较χ2=8.6771（P =0.0032）；两组需再次手术患者例数比较χ2=11.9114（P =0.0006）；两组有效患者例数比较χ2=14.4866（P =0.0001）。两组患者手术时间比较t =7.9142（P =0.0000）；两组患者住院时间比较t =6.0797（P =0.0000）；两组患者血尿时间比较t =5.2690（P =0.0000）；两组BUN水平比较t =1.3569（P =0.1788）；两组Cr水平比较t=4.3967（P =0.0000）。两组患者术后恶心、呕吐例数比较χ2=6.7818（P =0.0092）；两组患者术后发热例数比较χ2=8.2611（P =0.0041）；两组患者术后血尿例数比较χ2=8.6771（P =0.0032）；两组患者术后肾绞痛例数比较χ2=14.5142（P =0.0001）。结论 输尿管封堵器联合气压弹道碎石治疗输尿管结石，能提高碎石成功率，值得临床上广泛应用。

Abstract:

【Objective】 To explore the clinical efficacy of occluder combined with pneumatic lithotripsy in treatment of ureteral calculi. 【Methods】 Selected 78 cases of ureteral calculi treated in our hospital were randomly divide into observation group (40 cases) and control group with (38 cases), the control group using pneumatic lithotripsy, the observation group with ureteral occluder combined pneumatic lithotripsy. The operation time, operation time and hospitalization time, hematuria after treatment BUN, Cr changes in the water level were compared in two groups of patients ;And the adverse reactions incidence of the two groups patients was analyzed. 【Results】 The comparison of one-off lithotripsy in two groups was χ2 =5.5038 (P =0.0190); the comparison of clearance rates of calculus with one month in two group was χ2 =11.9114 (P =0.0006); the comparison of numbers of patients requiring reoperation reached χ2 =11.9114 (P =0.0006); he comparison of cases of effective patients in two groups achieved χ2 =14.4866 (P =0.0001). The comparison of operation duration in two groups were t =7.7914 (P =0.0000); the comparison of the stay length of patients in two groups was t =6.0797(P =0.0000); the comparison of hematuria duration of patients in two groups was t =5.2690 (P =0.0000); the comparison of BUN level of patients in two groups was t =1.3569 (P =0.1788); the comparison of Cr level of patients in two group was t =4.3967 (P =0.0000). The comparison of postoperative nausea and vomiting cases of patients was χ2 =6.7818 (P =0.0092); the comparison of the number of cases of patients with postoperative fever was χ2 =8.2611(P =0.0041); the comparison of the number of patients with postoperative hematuria was χ2 =8.6771 (P =0.0032); and the comparison of cases of patients with postoperative renal colic were was χ2 =14.5142(P =0.0001). 【Conclusion】 The treatment of ureter occluder combined pneumatic lithotripsy on the ureteral calculus is capable of improving the success rate of the lithotripsy, and it worths widely applying in clinical practices.