Abstract:【Objective】 To discuss the way of establishing and dividing operating space and its practical significance of laparoscopic thyroidectomy and parathyroidectomy. 【Methods】 120 cases of thyroidectomy, 3 cases of parathyroidectomy, in the process of establishing the operation space, the space from chest wall to the thyroid rear is divided into four parts named 1st, 2nd, 3th and 4th sub-space, lay stress on space limits, signs and essentials of every step. 【Results】 Operation time was 105~205 min, average 130 min; the amount of bleeding during 5~40 mL, average 20 mL; postoperative wound drainage amount 30~135 mL, average 75 mL, after 1~4 d extubation, all cases were proved by pathological diagnosis after operation, follow-up of 1 months to 2 years, no obvious chest wall wound pain, numbness, 2 cases of cervical and thoracic skin tight discomfort, no skin ecchymosis necrosis or effusion hematoma infection, no convulsions, 1 case of hoarseness, return to normal after 2 months. The hospitalization time was 3~6 d, average 4.5 d. Patients t are satisfactory on the beauty effects. 【Conclusion】 Division operating space, especially the Posterior-triangle concept can make operational doctors more profound and accurate understanding of space and every step of the operation, as is a method worthy of popularization and application.