120和70W 2μm激光剥橘式前列腺切除术治疗症状性前列腺增生的疗效对比研究

Comparison of 120W versus 70W thulium laser resection of the prostate-tangerine technique in treatment of symptomatic benign prostatic hyperplasia

摘要:

目的 比较研究120和70W 2μm激光剥橘式前列腺切除术（TmLRP-TT）治疗症状性前列腺增生（BPH）的有效性和安全性。方法 81例患者分为两组分别应用70和120W激光进行TmLRP-TT，对两组患者的围手术期和术后预后及并发症进行比较。结果 120 W较70 W TmLRP-TT在手术时间[（32.90±10.68）vs （62.55±23.66）min，P <0.001]和灌注液的用量[（18.34±6.68） vs （30.78±10.01）L，P =0.000]方面具有明显的优势。两组患者术后下尿路症状均明显改善，在治疗效果和并发症方面两组之间差异无显著性。 结论 70和120 W TmLRP-TT治疗症状性前列腺增生是安全有效的。另外120 W较70 W TmLRP-TT具有更高的汽化切除效率，所需灌注液更少，手术操作时间更短。

Abstract:

【Objective】 To compare the efficacy and safety of 120 W versus 70 W thulium laser resection of the prostate-tangerine technique (TmLRP-TT) for treatment of patients with symptomatic benign prostate hyperplasia (BPH). 【Methods】 81 patients of symptomatic BPH were randomized into 120W(n=41) and 70 W(n=40) TmLRP-TT groups. Data of peri- and postoperative parameters and complications were compared. 【Results】 120 W TmLRP-TT was significantly superior to 70 W device in terms of operation time[(32.90 ± 10.68) min vs (62.55 ± 23.66 min, P <0.001) ]and irrigation solution volume[(18.34 ± 6.68 L) vs (30.78 ± 10.01 L, P =0.000)]. Patients of both groups resulted in significant improvements in lower urinary tract symptoms, but there is no significant difference in therapeutic effect and complications between two groups. 【Conclusion】 70 W and 120 W TmLRP-TT were both efficient and safe for treating symptomatic BPH; moreover, the 120 W TmLRP-TT offered significantly higher vaporesection rates, less volume of intra-operative irrigation solution and shorter operation time than the 70 W device.