Abstract:【Objective】 To investigate the operative methods, effects, and clinical value of retroperitoneoscopic nephrectomy inside the fatty renal capsule for tuberculous nonfunctioning kidneys. 【Methods】 Retroperitoneescopic nephrectomy was performed on 10 cases, 7 of whom had the lesion on the left kidney and 3 on the right. Clinical presentations appeared with repeated fever, irritative symptoms, lumbago, painful or painless hematuria and pyuria. It is suggested that one kidney was nonfunctional or tuberculous kidney severely damaged while the other side is in normal function or compensated well, Diagnose them with urinal AFB, tuberculosis PCR, Urine mycobacterium tuberculosis culture, urinary color ultrasound, IVU, CT, ECT etc. before operations. 8 cases were diagnosed as tuberculous nonfunctioning kidneys and 2 were nonfunctional nephrarctias. Among these cases, 2 were combined with renal calculi, one was tuberculosis of epididymis, and another was contracture of bladder and the last one was adrenal tumor. Retroperitoneoscopic nephrectomy was practiced after 2 weeks to 2 months therapy of triple anti-tuberculosis medicine. 【Results】 All operations were performed successfully except 2 cases were taken to open operations for serious renal arteriovenous adhesion around. The operation time was 80~150 min (mean 117 min); the blood loss volume was 10~180 mL (mean 62.5 mL) and stay in hospital after operation about 4~8 days (average 5.5 days). Postoperative pathologic diagnosis showed 7 cases were nephrotuberculosis and 3 cases were chronic pyelonephritis. Keep anti-tuberculosis therapy for 6 months after operations. 10 patients showed satisfactory effects in the following 6~12 months. 【Conclusion】 It is the vital key to achieve the range and plane of dissecting and dispose of the renal pedicle safely for retroperitoneoscopic nephrectomy for tuberculous nonfunctioning kidneys. Separating renal tuberculosis inside the fatty renal capsule has advantages of minimal invasion, 1ess blood loss and quicker recovery.