Abstract:【Objective】 To investigate the effect of thoracoscopic splanchnicectomy for managing intractable pain in liver cancer patients. 【Method】 From March 2007 to September 2011, 8 patients with intractable pain of liver cancer were given the left side thoracoscopic splanchnicectomy. The duration and the complication of the operation were observed. The VAS pain scores were measured before the operation and at the 1st day, the 7th day, the 1st month after it. And the using of anodyne was recorded. 【Results】 Duration of surgery was 25~60min, average 35 min. Hospitalization time 5~7d, average 5.6d. The postoperative pain scores at the different time points of the patients were significantly decreased compared with that of preoperative ones. The VAS pain scores at the time of before the operation and at the 7th day, the 1st month after it was (8.92±1.06), (1.74±0.89), (1.95±1.03), respectively. No postoperative patients need opioid analgesics. 6 patients did not need any painkillers. 【Conclusion】 The thoracoscopic splanchnicectomy with sympathectomy is comparatively effective in the treatment of liver cancer pain.