Abstract:【Objective】 To evaluate the clinical value of laparoscopic simple prostatectomy compared with transurethral plasmakinetic enucleation of prostate(PKEP) simple prostatectomy for benign prostate hyperplasia(BPH). 【Methods】 The clinical data of laparoscopic and PKEP simple prostatectomy for large prostatic adenomas were retrospectively analyzed.Operating time,perioperative blood loss,postoperative irrigation time and duration of catheterization, hospital stay, analgesics usage, total cost of hospitalization,return to normal activity time,complication and postoperative parameters of Quality of International Prostate Score Symptoms(IPSS), Quality of Life questionnaires(QOL) and Maximum Flow Rate(Qmax) were compared between the two groups. 【Results】 In the laparoscopic prostatectomy and PKEP group, the parameters of blood loss during operation,postoperative irrigation time and duration of catheterization, analgesics use after operation, hospital stay after operation, return to normal activity time and the total cost of hospitalization were no significant difference(P >0.05). The postoperative parameters of IPSS, QOLand Qmax were significantly improved than that of perioperative of each group(P <0.01). Operating time was significantly less in the PKEP group than in the laparoscopic group(P <0.05). 【Conclusions】 The two surgical procedures have significant efficacy in the treatment of large BPH. But the operating time of PKER has more superiority than those of laparoscopy, so PKER deserves application.