维生素饮料溶解复方聚乙二醇电解质散对结肠镜检查患儿服药依从性及耐受性的影响

The effect of vitamin beverages in dissolving polyethylene glycol-electrolyte solution on medication compliance and tolerance in children undergoing colonoscopy

摘要:

目的 探讨维生素饮料（脉动）溶解复方聚乙二醇电解质散（PEG-ELS）对结肠镜检查患儿服药依从性及耐受性的影响。方法 选取2024年1月－2025年6月该院消化内科收治的243例结肠镜检查患儿为研究对象，采用便利抽样法分为干预组（124例）和对照组（119例），对照组使用温水溶解PEG-ELS，干预组使用脉动+温水（1∶1）溶解PEG-ELS；比较两组患儿口感满意度、服药依从性、服药时长、不良反应、实验室指标、排便次数及肠道准备质量。结果 干预组对缓泻药物口感满意度高于对照组，恶心、呕吐和低血糖症状发生率低于对照组，服药时间短于对照组，服药依从性高于对照组，差异均有统计学意义（P < 0.05）。两组患儿排便次数、肠道准备质量和实验室指标比较，差异均无统计学意义（P > 0.05）。结论 维生素饮料（脉动）溶解PEG-ELS可改善缓泻药口感，减少不良反应的发生，缩短服药时长，提高服药依从性，且不影响肠道准备质量及实验室指标。值得应用于临床。

Abstract:

Objective To explore the effect of a vitamin beverage (Mizone, a brand name) in dissolving polyethylene glycol-electrolyte solution (PEG-ELS) on medication compliance and tolerance in children undergoing colonoscopy.Methods A total of 243 children undergoing colonoscopy, who were admitted to the Department of Gastroenterology from January 2024 to June 2025, were selected as the research subjects. They were divided into an intervention group (n = 124) and a control group (n = 119) using the convenience sampling method. In the control group, PEG-ELS was dissolved in warm water. In the intervention group, PEG-ELS was dissolved in Mizone (a brand of vitamin beverage) plus warm water at a ratio of 1∶1. The two groups were compared in terms of taste satisfaction, medication compliance, medication administration duration, adverse reactions, laboratory indicators, frequency of defecation, and quality of bowel preparation.Results The intervention group had higher taste satisfaction with the laxative than the control group, lower incidence rates of nausea, vomiting, and hypoglycemic symptoms than the control group, a shorter total medication administration duration than the control group, and higher medication compliance than the control group, the differences were statistically significant (P < 0.05). Meanwhile, there were no significant effects on the frequency of defecation or the quality of bowel preparation and laboratory indicators (P > 0.05).Conclusion Dissolving the PEG-ELS in a vitamin beverage (Mizone, a brand of vitamin beverage) can improve the taste of the laxative, reduce the occurrence of adverse reactions, shorten the medication administration duration, and enhance medication compliance, without affecting the quality of bowel preparation or laboratory indicators. It is worthy of clinical application.