Abstract:Objective To evaluate the clinical efficacy and safety of cap-aspiration lumpectomy (CASL) for the treatment of gastric submucosal tumors (SMT).Methods A retrospective analysis was conducted on the clinical data of 161 patients with gastric SMT who received CASL treatment from June 2018 to September 2024. Evaluate the en bloc resection rate, operation time, and intraoperative and postoperative complications.Results All 161 patients successfully completed the surgery, and the total resection rate was 96.9% (156/161). The operation time was 7 to 30 minutes, with an average of (17.8 ± 6.6) minutes. The bleeding rate requiring intervention during the operation was 2.5%, and there were no cases of delayed perforation or death. Postoperative pathology was most commonly gastrointestinal stromal tumor (52.8%). During the follow-up period, the overall recurrence rate was 1.9%.Conclusion CASL treatment for gastric SMT is simple to operate, takes a short time, and has a high en bloc resection rate and safety. It is an efficient and reliable minimally invasive treatment method.