Abstract:Objective To evaluate the feasibility, safety, and short-term outcomes of single-port robot-assisted laparoscopic cholecystolithotomy for patients with solitary gallstones.Methods The clinical data of 50 patients with solitary gallstones who underwent single-port robot-assisted laparoscopic cholecystolithotomy from January 2025 to June 2025 in our hospital were retrospectively analyzed. Surgery-related conditions, postoperative complications, and postoperative recovery were recorded.Results All operations were completed successfully without conversion to multi-port laparoscopy or laparotomy. Operative time was 25 ~ 66 minutes, mean (41.5 ± 10.7) min; the time for suturing the gallbladder incision was 10 ~ 25 minutes, with an average of (16.0 ± 4.0) min; blood loss was 3 ~ 15 mL, mean (7.0 ± 2.9) mL. Postoperative hospital stay was 2 ~ 5 days, mean (3.1 ± 0.7) d. The incidence of complications was relatively low with 8.0% (4/50), all of which were minor. They included two cases of fever and two cases of mild redness and swelling at the incision site. All recovered after appropriate treatment and no serious complications occurred. The umbilical incision has healed well. The Vancouver Scar Scale (VSS) score indicated good scar quality, and the patient had a relatively high overall aesthetic satisfaction. Four months after the surgery, a follow-up ultrasound examination showed no residual stones.Conclusion Under the premise of strictly selecting indications, single-port robot-assisted laparoscopic cholecystolithotomy is safe and feasible. It features high operational flexibility, precise suturing, excellent cosmetic effect, and few short-term complications, providing a new option for gallbladder-preserving treatment.