Abstract:Objective To explore the clinical value of endoscopic diagnosis and treatment of duodenal bleeding of submucosal caliber-persistent artery with active bleeding.Methods A retrospective analysis was conducted on the clinical data of 6 patients diagnosed with duodenal bleeding of submucosal caliber-persistent artery and active bleeding by endoscopy from January 2015 to January 2023. Summarize the clinical manifestations, endoscopic features and treatment outcomes.Results Emergency endoscopic examination was completed within 24 hours, confirming that all 6 cases were simple duodenal bleeding of submucosal caliber-persistent artery, and endoscopic titanium clip hemostasis treatment was successfully performed.Conclusion Endoscopy has high value in diagnosing massive hemorrhage caused by duodenal bleeding of submucosal caliber-persistent artery. In addition, timely adoption of active and effective intervention measures under endoscopy can quickly stop bleeding and reduce the mortality rate. It is worth applying in clinical practice.