Abstract:Objective To observe the influence of preoperative oral administration of carbohydrate electrolyte solution on the comfort and gastric volume of patients undergoing painless colonoscopy.Methods A total of 120 patients who were scheduled to undergo elective painless colonoscopy from July 2024 to December 2024 were selected and the patients were divided into the observation group (oral carbohydrate electrolyte solution group) and the control group by the random number table method, 60 cases each. Record the relevant conditions of the examination [cross sectional area (CSA), gastric volume, inferior vena cava collapse index (IVC-CI) and colonoscopy time]. Record the mean arterial pressure (MAP), heart rate (HR), and percutaneous arterial oxygen saturation (SpO2) at the beginning of the examination (T1), the end of the examination (T2), and the time of discharge (T3). The visual analogue scale (VAS) scores for thirst and hunger, the degree of abdominal bloating (Likert score), and the self-rating anxiety scale (SAS) of all patients were recorded at 2 hours before the examination (T0), T1, and T3 time points. Record the recovery time, the duration of stay in the postanesthesia care unit (PACU), the Christensen fatigue score at the time of discharge and the satisfaction score. Record the usage of vasoactive drugs and the volume of fluid infusion. Observe the occurrence of adverse events such as hypotension, bradycardia and gastrointestinal symptoms.Results At time point T1, there was no statistically significant difference in CSA and gastric volume between the two groups of patients (P > 0.05). The IVC-CI in the observation group was significantly lower than that in the control group, and the difference was statistically significant (P < 0.05). There was no statistically significant difference in the colonoscopy examination time between the two groups of patients (P > 0.05). There was no statistically significant difference in MAP and HR between the two groups of patients at time point T1, and in SpO2 at time points T1, T2 and T3 (P > 0.05). The MAP and HR of the observation group at time points T2 and T3 were significantly higher than those of the control group, and the differences were statistically significant (P < 0.05). Compared with time point T0, the VAS score for thirst and hunger, SAS score and Likert score of the control group at time points T1 and T3 were significantly increased. The VAS scores for thirst and hunger, as well as the SAS scores at time points T1 and T3 in the observation group, were significantly decreased, while the Likert score was significantly increased. The differences were statistically significant (P < 0.05). The VAS scores for thirst and hunger, SAS scores and Likert scores of the observation group at time points T1 and T3 were significantly lower than those of the control group, and the differences were statistically significant (P < 0.05). The usage of deoxyepinephrine and atropine in the observation group was significantly less than that in the control group, the PACU stay time was significantly shorter than that in the control group, the Christensen fatigue score at discharge was significantly lower than that in the control group, and the patient satisfaction score was significantly higher than that in the control group. The differences were all statistically significant (P < 0.05). There was no statistically significant difference in the fluid infusion volume and anesthesia recovery time between the two groups of patients (P > 0.05). The incidences of hypotension, bradycardia, nausea and vomiting, and abdominal pain in the observation group were significantly lower than those in the control group, and the differences were statistically significant (P < 0.05).Conclusion The first 2 h before the examination of oral carbohydrate electrolyte fluid is taken, which can obviously reduce the degree of thirst, hunger and abdominal bloating in the perioperative period, relieve anxiety, improve patient satification. And the patient's blood flow dynamic is stable, the postoperative recovery time is short, it can relieve postoperative fatigue, optimize the patient experience. It deserves clinical promotion.