Abstract:Objective To analyze the effectiveness and safety of endoscopic thyroidectomy through the areola approach for thyroid carcinoma.Methods From January 2020 to June 2022, 100 patients with thyroid carcinoma were grouped into group A (n = 50, endoscopic thyroidectomy via axillary approach) and group B (n = 50, endoscopic thyroidectomy via areola approach) using a random number table method. The intraoperative and postoperative indicators, aesthetic effects, complications, and survival rate of the two groups were compared.Results The surgical time of group B was longer than that of group A, the intraoperative bleeding and postoperative drainage volume were more than those of group A, the differences were statistically significant (P < 0.05); There was no statistically obvious difference in the number of lymph node dissections, postoperative extubation time, length of hospital stay, Vancouver scar scale (VSS) score, survival rate, and total incidence of complications between the two grousps (P > 0.05).Conclusion Endoscopic thyroidectomy through the areola approach for thyroid carcinoma is similar to endoscopic thyroidectomy through the axillary approach in terms of the number of lymph node dissections, postoperative extubation time, hospital stay, aesthetic effect, complications, and survival rate, but the operation time is longer, the intraoperative blood loss is more, and the postoperative drainage is also more. Clinically, the appropriate surgical approach can be selected according to the actual situation.