Abstract:Objective To investigate the effectiveness and safety of biological patch in minimally invasive inguinal hernia surgery.Methods From July 2019 to July 2021, 100 inguinal hernia patients were divided into two groups based on the actual type of patch received. Biological patch was used in the experimental group (50 cases), and polypropylene patch was used in the control group (50 cases). The operation method was laparoscopic transabdominal preperitoneal (TAPP) hernia repair. Operating time, bleeding volume during operation, hospital stay after operation, hernia recurrence rate, incision infection rate, patch infection rate, and complication rate were compared between the two groups.Results Two groups of patients had no recurrence of hernia within 3 years after surgery, and didn't experience incision infection or patch infection after surgery. There were no significant differences in operating time, bleeding volume during operation, hospital stay after operation, seroma rate and chronic pain rate between the two groups (P > 0.05). The incidence rate of foreign body sensation in the control group was higher than that in the experimental group, with statistical difference (P < 0.05).Conclusion In conclusion, biological patch is safe and effective in laparoscopic TAPP hernia repair, and can reduce the incidence of postoperative foreign body sensation, providing a new option for laparoscopic inguinal hernia repair.