Abstract:Objective To investigate the impact of arthroscopic assisted locking hollow screw fixation on knee joint function and pain factors in patients with tibial plateau fractures.Method 113 patients with tibial plateau fractures from June 2021 to June 2023 were selected. According to different surgical methods, the patients were divided into arthroscopic group (57 cases) and traditional group (56 cases). The arthroscopic group was treated with arthroscopic assisted locking hollow screw fixation, while the traditional group was treated with open reduction and internal fixation. Compare the surgical status, postoperative recovery, and incidence of complications between two groups of patients, as well as the changes in pain factor levels before and after 24 hours of surgery, knee joint function before and 6 months after surgery, and changes in knee joint range of motion 6 months after surgery.Results The results showed that the arthroscopic group had significantly shorter surgical time and less intraoperative bleeding compared to the traditional group, with statistically significant differences (P < 0.05); The serum levels of 5-hydroxytryptamine (5-HT), substance P (SP), and prostaglandin E2 (PGE2) were significantly higher in both groups of patients 24 hours after surgery than those before surgery, but the arthroscopic group was significantly lower than that in traditional group, and the differences were statistically significant (P < 0.05); The arthroscopic group had significantly shorter postoperative mobilization time, hospitalization time, weight-bearing time, and fracture healing time compared to the traditional group, and the differences were statistically significant (P < 0.05); There was no statistically significant difference in Knee Society score (KSS) clinical score, KSS functional score, and hospital for special surgery knee score (HSS) between the two groups of patients 6 months after surgery (P > 0.05); The knee joint extension and flexion in the arthroscopic group were significantly greater than those in the traditional group 6 months after surgery, and the differences were statistically significant (P < 0.05); The postoperative incision infection in the arthroscopic group was significantly less than that in the traditional group, and the difference was statistically significant (P < 0.05).Conclusion Arthroscopic assisted locking hollow screw fixation is effective in treating tibial plateau fractures, significantly improving knee joint function and inhibiting pain factor release. It is worthy of clinical promotion and application.