蓝激光成像技术联合放大内镜与白光内镜诊断食管胃连接部病变的价值

Comparative study of blue Laser imaging combined with magnifying endoscope and white light endoscope in the detection of esophagogastric junction lesions

摘要:

目的 探讨蓝激光成像技术联合放大内镜（BLI+ME）诊断食管胃连接部（EGJ）病变的价值。方法 回顾性分析2022年2月－2024年2月该院接受电子胃镜检查的6 803例患者的内镜和病理资料，根据检查时所用胃镜型号的不同，将其分为BLI＋ME组（2 931例）和白光内镜组（WLI组，3 872例）。比较两组患者EGJ活检率、活检阳性率、总体病变检出率和早期诊断率等差异。结果 BLI + ME组EGJ的活检率为27.60%，活检阳性率为68.73%，总体病变检出率为20.74%，非癌性病变检出率为20.30%，早癌检出率为0.14%，齿状线上非癌性病变检出率为5.53%，齿状线下非癌性病变检出率为14.77%，齿状线下癌性病变检出率为0.27%，明显高于WLI组EGJ的活检率17.74%、活检阳性率60.26%、总体病变检出率11.90%、非癌性病变检出率11.67%、早癌检出率0.00%、齿状线上非癌性病变检出率3.49%、齿状线下非癌性病变检出率8.19%和齿状线下癌性病变检出率0.05%，两组患者上述指标比较，差异均有统计学意义（P < 0.05）。结论 BLI联合ME能够提高EGJ的活检率、活检阳性率、总体病变检出率、非癌性病变检出率、早癌检出率、齿状线上、下非癌性病变检出率和齿状线下癌性病变的检出率，有助于提高EGJ病变的早期诊断率和早期治疗率。值得临床推广应用。

Abstract:

Objective To explore the applicative value of blue Laser imaging combined with magnifying endoscope (BLI+ME) system for the lesion of esophagogastric junction (EGJ).Methods Retrospective study endoscopic and pathological reported during February 2022 to February 2024. 6 803 patients who met the inclusion and exclusion criteria were enrolled. They were divided into BLI+ME group (2 931 cases) and white light imaging group (WLI group, 3 872 cases) according to the different gastroscopy types used in the examination. Finally, the EGJ biopsy rate, positive biopsy rate, detection rate of various lesions and early diagnosis rate between the two groups were compared.Results The biopsy rate of the BLI + ME group was 27.60%, the positive biopsy rate was 68.73%, and the detection rate of all the lesions was 20.74%, the detection rate of non-cancerous lesions was 20.30%, the detection rate of early cancer was 0.10%, the detection rate of non-cancerous lesions above the dentate line was 5.53%, the detection rate of non-cancerous lesions below the dentate line was 14.77%, the detection rate of cancerous lesions below the dentate line was 0.27%, significantly higher than those of the WLI group, which the biopsy rate was 17.74%, the positive biopsy rate was 60.26%, and the detection rate of all the lesions was 11.90%, the detection rate of non-cancerous lesions was 11.67%, the detection rate of early cancer was 0.00%, the detection rate of non-cancerous lesions above the dentate line was 3.49%, the detection rate of non-cancerous lesions below the dentate line was 8.19%, the detection rate of cancerous lesions below the dentate line was 0.05%, the differences were statistically significant (P < 0.05).Conclusion The BLI+ME system can enhance the biopsy rate, positive biopsy rate, the detection rate of all the lesions, early cancer detection rate, non-cancerous lesions detection rate above and below the dentate line, and cancerous lesions detection rate below the dentate line at the EGJ. It is helpful to improve the early diagnosis rate and early treatment rate of EGJ. It is worthy of clinical application.