Abstract:Objective To analyze the curative effect of unilateral biportal endoscopy (UBE) transforaminal lumbar interbody fusion (TLIF) and its influences on the recovery of lumbar function in lumbar spinal stenosis (LSS).Methods 70 patients with secondary LSS were retrospectively analyzed between September 2021 and September 2023. According to different surgical methods, they were divided into UBE-TLIF group (39 cases) and TLIF group (31 cases). The occurrence of postoperative complications during follow-up, surgical indexes (operation time, postoperative leaving bed time, and hospitalization time), hemoglobin level before surgery and 3 and 7 d after surgery, improvement rate of dural sac cross-sectional area (DSCA) at 3 d after surgery, the visual analogue scale (VAS) and Oswestry disability index (ODI) at different time points were compared between the two groups.Results The operation time, postoperative leaving bed time and hospitalization time in UBE-TLIF group were shorter than those in TLIF group, the differences were statistically significant (P < 0.05). At 3 d after surgery, improvement rate of DSCA in UBE-TLIF group was higher than that in TLIF group, the difference was statistically significant (P < 0.05). At the 3 d and 7 d after surgery, hemoglobin level was decreased in both groups, which was higher in UBE-TLIF group than TLIF group, the difference was statistically significant (P < 0.05). At 3 d, 1 month and 3 months after surgery, VAS and ODI in both groups were decreased than those before the surgery, which were lower in UBE-TLIF group than TLIF group, the differences were statistically significant (P < 0.05). The incidence of postoperative complications in UBE-TLIF group was lower than that in TLIF group (7.69% vs 25.81%), the difference was statistically significant (P < 0.05).Conclusion The curative effect of UBE-TLIF is better in patients with secondary LSS, which can significantly relieve pain, achieve full lumbar decompression and promote the recovery of lumbar function. It is worthy clinical application.