Abstract:Objective To investigate the clinical effect and safety of endoscopic inlay butterfly cartilage tympanoplasty (BCT) by day surgery mode.Method 120 patients with tympanic membrane perforation from June 2021 to June 2022 were randomly divided into two groups, the observation group of 60 patients underwent endoscopic inlay BCT, the control group of 60 patients underwent endoscopic tympanic membrane repair with tragus cartilage membrane. Both groups of patients completed all preoperative examinations in the outpatient department and completed the steps of admission, surgery, and discharge within 24 h. The surgical conditions (operation time and intraoperative blood loss), pure tone average (PTA) after 6 months, air-bone gap (A-B gap) after 6 months, tympanic membrane healing rate, and complications were compared between the two groups.Results There was no statistical significance in the operation time and intraoperative blood loss between the observation group and the control group (P > 0.05). After 6 months, the PTA and A-B gap of both groups were lower than those before the surgery (P < 0.01), the observation group had a significantly lower PTA (23.40 ± 4.40) dB HL and A-B gap (9.11 ± 3.13) dB HL than the control group (29.12 ± 3.33) dB HL and (14.86 ± 3.20) dB HL, with statistically significant differences (P < 0.05). There was no statistical significance in the tympanic membrane healing rate between the two groups after surgery (P > 0.05), but the incidence of complications in the observation group was 5.0% (3/60), significantly lower than that in the control group (21.7%, 13/60), with a statistically significant difference (P < 0.05).Conclusion Endoscopic inlay BCT is safe and effective in the treatment of tympanic membrane perforation, with better hearing recovery than tragus cartilage membrane repair surgery, fewer complications, and more suitable for day surgery mode. It is worthy clinical application.