Abstract:Objective To explore the validity and security of treatment of different operation approach under nasal endoscope in patients with benign maxillary sinus lesions.Methods A retrospective analysis was performed on 80 patients with benign maxillary sinus lesions diagnosed and treated from January 2020 to January 2022, and they were divided into group A (n = 40) and group B (n = 40) according to the operative method. Group A was treated with middle nasal meatus combined with Caldwell-Luc operation under nasal endoscope, and group B was treated with middle nasal meatus antrostomy first and anterior lacrimal recess approach later under nasal endoscope. The clinical efficacy, operation index, visual analogue scale (VAS), Lund-Kennedy endoscopic score, adverse reactions and recurrence rate of both groups were compared before and after operation.Results The total effective rate was sensibly higher in group B than that in group A, the intraoperative blood loss was sensibly less in group B than that in group A, the operation and hospitalization time were sensibly shorter in group B than those in group A, 6 months after operation, the VAS and Lund-Kennedy scores were sensibly decreased in comparison with those before operation, and group B was sensibly decreased in comparison with those in group A, the total incidence rate of adverse reactions and recurrence rate were sensibly lower in group B than those in group A, the differences were statistically significant (P < 0.05).Conclusion The surgical treatment of patients with benign maxillary sinus lesions through the middle nasal meatus and the anterior lacrimal recess approach under nasal endoscope is effective and can relieve the pain of patients with high safety. It is worthy of clinical application