Abstract:Objective To study the effect of knee arthroscopy+unicondylar joint replacement on knee joint function in patients with anteromedial compartment knee osteoarthritis in different periods.Methods A retrospective analysis of the clinical data of 100 patients with anteromedial compartment knee osteoarthritis from October 2015 to October 2019. All the patients underwent knee arthroscopy+unicondylar joint replacement, of which 56 patients underwent concurrent treatment was the observation group (Outerbridge grading were Ⅲ~Ⅳ level), and 44 patients underwent staged treatment as the control group (Outerbridge grading were Ⅰ to Ⅱ level). Compared the clinical efficacy and clinical indicators of the two groups, compared the knee joint range of motion before treatment and 3, 6, and 12 months after treatment, and analyzed the knee function scores of the two groups before and after treatment [pain visual analogue scale (VAS), Oxford knee score (OKS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score] changes, and compared the postoperative complications of the two groups.Results The total effective rate of the observation group was 94.64%, which was not statistically different from 88.64% of the control group (P > 0.05). The operation time and hospital stay in the observation group were shorter than those in the control group (P < 0.05). 3, 6 and 12 months after treatment in the two groups, the range of motion of the knee joint was higher than that before treatment (P < 0.05), however, there were no significant difference between the two groups (P > 0.05). Compared with before treatment, the VAS, OKS and WOMAC score in the two groups were decreased after treatment (P < 0.05); Compared with the control group, the WOMAC and OKS score in the observation group were lower than those after treatment (P < 0.05); The VAS was compared between the two groups, the difference was not statistically significant (P > 0.05). No serious complications occurred in the two group, and there was no statistical significance in the incidence of complications between the two groups (P > 0.05).Conclusion In the same period and staged knee arthroscopy+unicondylar joint replacement, the effect of knee osteoarthritis patients with the anterior medial compartment is equivalent, however, simultaneous knee arthroscopy combined with unicondylar jiont replacement can promote the recovery of knee joint function, which is worthy of promotion.