Abstract:Objective To research the clinical utility value of self-made transparent cap during single colonoscopy.Methods 282 patients were enrolled and randomly divided into the self-made transparent cap group (n = 140) and the control group (n = 142) based on the inclusion and exclusion criteria. All the patients were chosen from the same department and the same hospital, and all single colonoscopy procedures were performed by one experienced physician with senior professional title. General clinical information, location, number and diameters of detected polyps, time of ileocecal valve insertion and withdrawal time were collected and compared between the two groups.Results The self-made transparent cap groups insertion time (6.21 ± 2.43) min was shorter than that in the control group (6.85 ± 2.71) min (P < 0.05). Nevertheless, in the achievement rate of cecal insertion and colonoscopy retreat time between the two groups, there were no significant differences (P > 0.05). The detection rate of polyps in the self-made transparent cap group was higher than that in the control group (47.86% vs 35.21%, P < 0.05). The detection rate of polyps with diameter ≤ 5 mm in the self-made transparent cap group was also higher (P < 0.05). In the ascending colon and sigmoid colon segments, the detection rate of polyps in the self-made transparent cap group was higher than that in the control group (P < 0.05). However, there were no differences in other segments. No complications (perforation and bleeding) were acquired in both groups.Conclusion The self-made transparent cap assisted colonoscopy can effectively reduce the entry time of ordinary single colonoscopy, improve the detection rates of both polyps in the ascending and sigmoid colon and polyps with diameter ≤ 5 mm. Moreover, the self-made transparent cap is cost-effective, which is more conducive for the promotion among primary hospitals.