单侧双通道脊柱内镜技术与传统后路腰椎椎间融合术治疗腰椎退行性疾病的临床疗效

Clinical effects of unilateral biportal endoscopic technique and traditional posterior lumbar interbody fusion in treatment of lumbar degenerative diseases

摘要:

目的 探讨单侧双通道脊柱内镜技术（UBE）与传统后路腰椎椎间融合术（PLIF）治疗腰椎退行性疾病的临床疗效。方法 选取2018年8月－2021年8月该院收治的腰椎退行性疾病患者80例，根据不同手术方式将患者分为研究组（n = 30）和对照组（n = 50），研究组行UBE，对照组行传统PLIF，比较两组患者手术相关指标、疼痛视觉模拟评分法（VAS）、日本骨科学会（JOA）评分、血清炎症因子水平及术后并发症发生情况。结果 研究组术中出血量和术后引流量均少于对照组（P < 0.05），术后住院时间短于对照组（P < 0.05）；研究组术后VAS、TNF-α和IL-6水平均低于对照组（P < 0.05），术后JOA评分及IL-4水平均高于对照组（P < 0.05）；研究组术后并发症总发生率为10.00%，对照组术后并发症总发生率为12.00%，两组患者比较，差异无统计学意义（P > 0.05）。结论 UBE治疗腰椎退行性疾病临床效果较好，可有效改善手术相关指标，降低炎症因子水平，减轻患者术后疼痛，且安全性好。

Abstract:

Objective To investigate the clinical effects of unilateral biportal endoscopic (UBE) technique and traditional posterior lumbar interbody fusion (PLIF) in treatment of lumbar degenerative diseases.Methods 80 patients with lumbar degenerative diseases from August 2018 to August 2021 were selected as the research subjects. Patients treated with UBE technique and those treated with traditional PLIF were defined as study group (n = 30) and control group (n = 50), respectively. Surgery-related indicators, visual analogue scale (VAS) of pain, Japanese Orthopaedic Association (JOA) score of low back pain, serum inflammatory factor levels and postoperative complications were compared between the two groups.Results The intraoperative blood loss and postoperative drainage volume of study group were less than those of the control group (P < 0.05), and postoperative hospital stay of study group was shorter than that of the control group (P < 0.05). After operation, the VAS, TNF-α and IL-6 levels of study group were lower than those of the control group (P < 0.05). The JOA score and IL-4 level were higher than those of the control group (P < 0.05). The incidence rate of postoperative complications in the study group and the control group were 10.00% and 12.00%, respectively (P > 0.05).Conclusion UBE technique is effective and safe in treatment of lumbar degenerative diseases. It can effectively improve surgery-related indicators and inflammatory factor levels, and alleviate postoperative pain, with safety.