Abstract:Objective To analyze the clinical efficacy of endoscopic dacryocystorhinostomy (En-DCR) in treating chronic dacryocystitis by laser-assisted ablation with annular cannula.Methods Clinical data of 36 patients with chronic dacryocystitis of 40 eyes were retrospectively analyzed. All the patients were treated with En-DCR laser ablation of leakage, during the operation, cannula and 5-fluorouracil were used. The cannula was removed 6 weeks after operation, and the initial clinical efficacy of this operation was observed.Results The patients were followed up for 6~12 months. Among the 40 eyes of 36 cases of chronic dacryocystitis, 36 eyes were cured (90.0%), 3 eyes were improved (7.5%) and 1 eye was invalid (2.5%). The effective rate was 97.5%.Conclusion The innovative use of semiconductor laser in En-DCR for ablation of leakage, annular cannula placement and combined application of 5-fluorouracil not only effectively reduced intraoperative bleeding, but also reduced the scar hyperplasia of granulation at leakage, and improved the surgical efficiency.