Abstract:Objective To investigate the effect of bronchoscope cytobrush on the removal of mucus plug in children with critical plastic bronchitis (PB).Methods The clinical data of 5 children with critical PB were retrospectively analyzed. Fiberoptic bronchoscope with combination of cytobrush and lavage was applied to the patients under general anesthesia and ventilator-assisted ventilation to remove the mucus plug in the bronchus.Results Mucus plug in the bronchus of 5 children in PICU were successfully removed by fiberoptic bronchoscopy, remained the stable condition during the operation procedure, including the vital signs and percutaneous arterial oxygen saturation (SpO2) (>80%). After bronchoscopy, all children received ventilator-assisted ventilation in PICU for within 2 days.Conclusion Fiberoptic bronchoscope with cytobrush could be one of the effective methods to remove mucus plug in the bronchus of children under general anesthesia and ventilation, with higher efficiency but less injury.