Abstract:Objective To investigate the value and safety of the clinical application of negative pressure device to locate the site of occult epistaxis.Methods In this study, 318 patients with occult rhinorrhea from August 2018 to July 2021 were retrospectively collected as the observation group, and 264 patients with occult rhinorrhea from August 2015 to July 2018 were used as the control group. In the observation group, patients were instructed to hold their breath and then apply a negative pressure suction device to induce nasal bleeding, and then apply nasal endoscopy to locate the bleeding site. In the control group, conventional nasal endoscopy was performed. The patients in both groups had their nasal bleeding sites stopped by electrocoagulation with an attractable electrode. The detection rate of nasal bleeding site, length of surgery, hospital stay, number of recurrent nasal bleeding cases, intraoperative pain, number of postoperative local adhesions in the nasal cavity, and number of postoperative cases of secretory otitis media were collected from both groups.Results The observation group had higher detection rate of nasal bleeding, significantly shorter operation length and hospital stay, fewer cases of recurrence, significantly less intraoperative pain, and fewer cases of postoperative nasal adhesions than the control group, and the differences were statistically significant (P < 0.05). In the observation group, no mucosal heterogeneous injury was seen at the non-bleeding site, and none of them had secretory otitis media at postoperative follow-up.Conclusion The application of negative pressure device to locate occult bleeding sites for the treatment of epistaxis is safe, effective, and worthy of clinical promotion.