耳内镜辅助下醋酸曲安奈德益康唑乳膏治疗外耳道真菌病的疗效分析
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1.杭州师范大学附属医院 耳鼻咽喉科,浙江 杭州 310015;2.杭州师范大学,浙江 杭州 311121

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解道宇,E-mail:xiedaoyu_2010@163.com

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Analysis of the curative effect of triamcinolone acetonide acetate econazole cream in treatment of otomycosis assisted by otoendoscope
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1.Department of Otolaryngology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang 310015, China;2.Hangzhou Normal University, Hangzhou, Zhejiang 311121, China

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    目的 探讨耳内镜辅助下醋酸曲安奈德益康唑乳膏治疗外耳道真菌病的疗效。方法 对349例外耳道真菌病患者进行耳内镜检查并清理,分为醋酸曲安奈德益康唑乳膏治疗组(观察组,n = 137)和无醋酸曲安奈德益康唑乳膏治疗组(对照组,n = 212)。观察组对患耳依次行3%过氧化氢清洗、生理盐水清洗和醋酸曲安奈德益康唑乳膏涂布,每天3次;对照组仅使用3%过氧化氢清洗或生理盐水清洗。分别于第3、7和14天复诊,比较两组患者治疗效果、复发率、耳内镜下清理外耳道次数和治愈时间。结果 观察组治疗后总有效率明显高于对照组(P < 0.05),复发率明显低于对照组(P < 0.05),耳内镜下清理外耳道次数和治愈时间均少于对照组(P < 0.05)。结论 耳内镜下醋酸曲安奈德益康唑乳膏治疗外耳道真菌病,有良好的治疗效果。

    Abstract:

    Objective To explore the therapeutic effect of triamcinolone acetonide acetate econazole cream in treatment of otomycosis assisted by otoendoscope.Methods 349 patients with otomycosis were examined by otoendoscope and divided into triamcinolone acetonide acetate econazole cream treatment group (observation group, n = 137) and no triamcinolone acetonide acetate econazole cream treatment group (control group, n = 212). The observation group included 3% hydrogen peroxide cleaning, saline cleaning and coating of triamcinolone acetonide acetate econazole cream 3 times daily. The control group was cleaned with only 3% hydrogen peroxide or with a saline solution. The visit returned on days 3, 7 and 14, respectively, and the treatment effect, recurrence rate, number of external auditory canal cleaning and cure time of the two groups were compared.Results The total efficiency in observation group was significantly higher than that in control group (P < 0.05), recurrence rate in observation group was significantly lower than that in control group (P < 0.05), and healing time of external ear canal in observation group were less than in control group (P < 0.05).Conclusion Triamcinolone acetonide acetate econazole cream under otoendoscope has good therapeutic effect on external auditory canal mycosis.

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周国文,柏志香,丁钟灵,王璐琦,丁吉女,解道宇.耳内镜辅助下醋酸曲安奈德益康唑乳膏治疗外耳道真菌病的疗效分析[J].中国内镜杂志,2022,28(9):66-72

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  • 收稿日期:2021-10-11
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  • 在线发布日期: 2022-09-27
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