Abstract:Objective To evaluate the effect of ultrasound-guided bilateral the thyrohyoid muscle and thyrohyoid membrane space block for awake fiberoptic bronchoscopy.Methods 60 patients scheduled for elective awake fiberoptic bronchoscopy were randomly selected and divided into two groups using a random number table: ultrasound-guided the thyrohyoid muscle and the thyrohyoid membrane bilaterally space group (group U, n = 30) and traditional group (group C, n = 30), nebulized 2% lidocaine was inhaled and cricothyroid membrane injection was adopted in both group for topical anesthesia before operation. Aged 65 ~ 80 years, weighed 45 ~ 80 kg, American Society of Anesthesiology (ASA) grade Ⅰ or Ⅱ. In group U, the probe was placed in a paramedian sagittal position to locate the hyoid bone and thyroid cartilage, and 1% lidocaine 3 mL was injected into the space between the thyrohyoid muscle and the thyrohyoid membrane bilaterally. Mean arterial pressure (MAP) , heart rate (HR) and percutaneous arterial oxygen saturation (SpO2) were recorded at the time of entering the room (T0), before fiberoptic bronchoscopy entering the mouth (T1), immediately after entering the glottis (T2), and 5 min after entering the trachea (T3). Ramsay sedation scores and patients’ comfort score were recorded.Results Compared with group C, MAP and HR decreased significantly at T2 in group U (P < 0.05), comfort score descreased significantly, the number of remedial cases decreased significantly, and the incidence of nausea, vomiting, cough and physical activity decreased significantly in group U (P < 0.05).Conclusion Ultrasound-guided the thyrohyoid muscle and the thyrohyoid membrane bilaterally space block can improve topical anesthesia efficacy of fiberoptic bronchoscopy, reduce the stress response of examination operation, improve the comfort of patients with seldom adverse reactions, meanwhile the incidence of postoperative hoarseness did not affect the patient's comfort.