内镜下逆行阑尾炎治疗术治疗急性阑尾炎疗效的Meta分析

Effect of endoscopic retrograde appendicitis therapy in treating patients with acute appendicitis: a Meta-analysis

摘要:

目的 评估内镜下逆行阑尾炎治疗术（ERAT）在急性阑尾炎治疗中的疗效。方法 通过计算机检索CNKI数据库、万方数据库、PubMed和谷歌学术中2017年－2020年ERAT治疗急性阑尾炎的相关文献，采用Review Manager 5.3.5统计软件进行数据处理，对纳入资料的异质性进行分析，计算OR＾值及95%CI。结果 按照入选标准，共纳入33项临床试验，2 729例患者。Meta分析结果显示：ERAT组住院时间和手术时间明显较传统手术组短（MD = -2.81，95%CI：-3.28～-2.34；MD = -20.24，95% CI：-22.63～-17.85），总并发症发生率明显较传统手术组低（OR＾ = 0.19，95%CI：0.13～0.26），体温恢复明显较传统手术组快（MD = -1.03，95%CI：-1.41～-0.65）。结论 ERAT是一种安全有效地治疗急性阑尾炎的方法，可缩短手术时间和住院时间，降低并发症发生率，具有临床推广价值。

Abstract:

Objective The efficacy evaluation of the endoscopic retrograde appendicitis therapy (ERAT) in the treatment of acute appendicitis.Methods We searched and got the literatures through computer retrieval from CNKI database, Wanfang database, PubMed and Google Academics from 2017 to 2020. Then adopted the Review Manager 5.3.5 software to do the statistical processing, analyze heterogeneity of the literatures, and calculate the OR＾ value and its 95%CI.Results According to the inclusion criteria, 33 clinical trials and the involved 2 729 patients were included. Meta-analysis showed that, the length of hospital stay (MD = -2.81, 95%CI: -3.28 ~ -2.34) and operation time (MD = -20.24, 95%CI:-22.63 ~ -17.85) in ERAT group were significantly shorter than those in traditional surgery group, and the total incidence of complications were significantly lower than that in traditional group (OR＾ = 0.19, 95%CI: 0.13~0.26), the body temperature recovery was significantly faster than that in traditional surgery group (MD = -1.03, 95%CI: -1.41 ~ -0.65).Conclusion ERAT is a safe and effective treatment for acute appendicitis, it can effectively shorten the operation time and hospitalization time, reduce the incidence of complications, and has significant value of clinical promotion.