Objective To summarize the perioperative management of ureteroscopy and flexible ureteroscopy in patients after cardiac transplantation.Methods Clinical data of 10 patients with ureteral calculi after cardiac transplantation from January 2008 to January 2021 were retrospectively analyzed.Results The operation was successfully completed in all 10 patients without serious complications. The stones disappeared in the follow-up one month after operation, and no other abnormalities were found. The transplanted heart is in good condition.Conclusion Through multidisciplinary cooperation and adequate perioperative preparation, ureteroscopy is safe and feasible for cardiac transplant recipients.