Abstract:Objective To evaluate the effect of ultrasound-guided posterior quadratus lumborum block (QLB) and subcostal transverse abdominis plane block (STAPB) in laparoscopic cholecystectomy (LC).Methods 60 patients with LC from June 2020 to December 2020 were selected, and were divided into QLB group (n = 30) and STAPB group (n = 30). Before induction of general anesthesia, bilateral ultrasound-guided posterior QLB was performed in QLB group and bilateral ultrasound-guided STAPB was performed in STAPB group, all the patients controlled intravenous analgesia was used after operation. The time of first walking after operation, the time of first pressing analgesia pump, the times of recovery of flurbiprofen axetil, the visual analogue scale (VAS) at 1, 4, 8, 12, 24 and 48 h after operation, the dosage of sufentanil in each period of perioperative period and the incidence of adverse reactions in 48 h after operation were observed.Results Compared with STAPB group, the time of first pressing analgesia pump in QLB group was longer, the first walking time was significantly shortened, the resting VAS score at 12 h after operation and the exercise VAS at 4, 8, 12 and 24 h after operation were significantly lower, and the consumption of sufentanil at 0~12 h, 12~24 h and 24~36 h after operation in QLB group was significantly decreased (P < 0.05); The total incidence of adverse reactions 48 hours after operation in QLB group was lower than that in STAPB group (P < 0.05).Conclusion Ultrasound-guided posterior QLB is more effective than ultrasound-guided STAPB in reducing the postoperative VAS, prolonging the analgesia time and reducing the use of opioids in perioperative period, so as to reduce the incidence of adverse reactions and accelerate the recovery of patients.