Abstract:Objective To investigate the clinical characteristics, treatment plan and prognosis of ischemic bowel disease caused by painless colonoscopy.Methods Clinical data of 7 422 patients who underwent colonoscopy or endoscopic treatment of intestinal polyps from January 2018 to December 2020 were retrospectively analyzed, they were divided into painless colonoscopy group (n = 4 615) and ordinary colonoscopy group (n = 2 807) according to the different examination method. To analyze the clinical characteristics of ischemic bowel disease caused by two examination methods.Results Two groups of patients with abdominal pain, hematochezia, fever as the main clinical manifestations, early medical treatment, all cured. A total of 41 patients were diagnosed with ischemic bowel disease, including 36 cases in the painless colonoscopy group and 5 cases in the ordinary colonoscopy group. There was statistically significant difference in ischemic bowel disease between the painless colonoscopy group and the ordinary colonoscopy group (χ2 = 11.51, P = 0.001). There was statistically significant difference in the incidence of ischemic bowel disease between patients with and without endoscopic polyp removal (χ2 = 30.75, P = 0.000). Painless colonoscopy and endoscopic polyp removal were independent risk factors for ischemic bowel disease (OR^ = 2.907, P = 0.032; OR^ = 3.313, P = 0.000).Conclusion Painless colonoscopy and intestinal polypectomy are more likely to induce the occurrence of ischemic bowel disease. Intervention as soon as possible after the occurrence of ischemic bowel disease, the prognosis is good.