Abstract:Objective To study the impact of different times of endoscopy on the detection rate of colorectal polyps and related factors.Methods 328 patients who underwent colonoscopy from December 2015 to December 2020 were included as the research objects, the detection rate of colorectal polyps was recorded, the detection rates of polyps with different times of endoscopy were compared. The Logistic analysis were used to analyze the related factors of missed diagnosis of colonoscopy.Results There were 368 colorectal polyps were found in 328 patients, the polyps were found in 284 patients during the first endoscopy. 296 pieces were detected, the detection rate was 80.43%, 66 pieces were newly detected in the second entry, and the detection rate was 91.67%. 4 pieces were newly detected in the third entry, and the detection rate was 66.67%. The detection rate of secondary endoscopy were significantly higher than that of the first, the difference were statistically significant (P < 0.05). There was no significant difference in the detection rate between secondary and tertiary endoscopy (P > 0.05). Logistic regression analysis showed that the number, diameter, shape and location of polyps were independent influence factors of missed diagnosis at the first endoscopy (P < 0.05). Logistic regression analysis showed that polyp shape and polyp location were independent influence factors of missed diagnosis by secondary endoscopy (P < 0.05).Conclusion The detection rate of colorectal polyps by secondary endoscopy is high, which is affected by the shape and location of polyps.