Abstract:Objective To compare the diagnostic value of linked color imaging (LCI) and white light imaging (WLI) in minor lesions in esophagogastric junction.Methods A prospective analysis was conducted on the patients who underwent LASEREO gastroscopy from September 2020 to February 2021, the patients were randomly divided into the LCI group and the WLI group, in which the esophagogastric junction in the WLI group was observed only with the WLI mode, and the esophagogastric junction in the LCI group was observed only with the LCI mode. The detection rate, biopsy rate and corresponding pathological conditions of minor lesions in the esophagogastric junction were compared between the two modes.Results The detection rate and biopsy rate of minor lesions in esophagogastric junction in the LCI group were higher than that in the WLI group (33.21% vs 25.24%, P = 0.033; 18.41% vs 11.82%, P = 0.025). Especially the detection of mucosal redness and 0 ~ Ⅱb type lesions in LCI group was significantly higher than that in WLI group (28.88% vs 21.41%, P = 0.036; 19.49% vs 13.42%, P = 0.046).Conclusion LCI can effectively improve the detection rate and biopsy rate of minor lesions in esophagogastric junction, especially for 0 ~ Ⅱb red type lesions, which is worthy clinical promotion and application.