肠道准备后2 h即行无痛肠镜检查的安全性及有效性研究

Safety and effectiveness of painless colonoscopy within 2 hours after bowel preparation

摘要:

目的 探讨肠道准备后2 h即行无痛肠镜检查的安全性及有效性。方法 将120名志愿者随机分为观察组和对照组，观察组行快速肠道准备，对照组行常规肠道准备。比较两组患者肠道准备过程中恶心、呕吐发生率、检查完成率、检查时长、检查过程中误吸发生率、息肉检出率和Boston肠道准备量表（BBPS）评分。结果 两组患者均全部完成检查，检查过程中无呕吐和误吸等不良事件发生。观察组和对照组平均检查时长分别为（15.50±4.41）和（17.07±4.43）min，息肉检出率分别为28.3%（17/60）和31.7%（19/60），两组比较，差异无统计学意义（P > 0.05）；观察组和对照组肠道准备过程中恶心、呕吐发生率分别为36.7%（22/60）和63.3%（38/60），BBPS评分分别为（8.88±0.32）和（8.63±0.55）分，两组比较，差异有统计学意义（P < 0.05）。结论 对于无消化道症状的健康体检者，在快速肠道准备情况下，肠道准备后2 h即行无痛肠镜检查，不会增加误吸发生率，也不影响肠道准备质量，且可明显降低肠道准备过程中恶心和呕吐等不良反应的发生率。

Abstract:

Objective To explore the safety and effectiveness of painless colonoscopy within 2 hours after bowel preparation.Methods 120 volunteers were randomly divided into observation group and control group. The observation group received rapid bowel preparation and the control group received conventional bowel preparation. The incidence of nausea and vomiting, the completion rate of the examination, the time-consuming of the examination, the incidence of aspiration during the examination, polyp detection rate and the Boston Bowel Preparation Scale (BBPS) scores were compared between the two groups during the bowel preparation process.Results The two groups of volunteers all completed the examination. During the examination, there were no adverse events such as vomiting or aspiration. The average examination time of the observation group and the control group were (15.50 ± 4.41) and (17.07 ± 4.43) min, the polyp detection rate was 28.3% (17/60) and 31.7% (19/60) respectively, there was no statistically significant difference between the two groups (P > 0.05). The incidences of nausea and vomiting during bowel preparation in the two groups were 36.7% (22/60) and 63.3% (38/60) respectively, and the BBPS scores were (8.88 ± 0.32) and (8.63 ± 0.55), respectively, there were statistically significant difference between the two groups (P < 0.05).Conclusion For healthy people who have no symptoms of digestive tract, in the case of rapid bowel preparation, a painless colonoscopy can be performed 2 hours after bowel preparation, which does not increase the chance of aspiration, does not affect the quality of bowel preparation, and can significantly reduce the nausea and vomiting during bowel preparation.