Abstract:Objective To explore the effectiveness and safety of a new technique for biliary cannulation in difficult cannulation during ERCP.Methods In the process of ERCP diagnosis and treatment, the snare assisted precut technique was used to assist bile duct intubation in 23 cases with difficult cannulation. The intubation time, success rate of intubation, intraoperative and postoperative complications were observed.Results 22 cases were successfully intubated. Intraoperative bleeding occurred in 1 case and stopped spontaneously. There was no pancreatitis, perforation or operation related death.Conclusion The snare assisted precut can fully expose the common bile duct, with clearer layers and simple operation, which can be used as an alternative to solve the difficult cannulation.