Abstract:Objective Summarize and analyze the problems and causes of nylon rope ligation device in endoscopic purse string suture, so as to improve and explore the skills and strategies in the use of nylon rope ligation device.Method The operation process, problems and causes of nylon rope ligation device in the use of 99 patients with upper gastrointestinal purse string suture from April 2017 to December 2020 were analyzed retrospectively.Results 21 problem events were summarized, including 10 folds at the front end of the outer sheath, 5 decoupling of the ligation ring, 2 failure to release the ligation ring, 2 disconnection of the ligation ring and 2 forward movement of the ligation ring plug. The results showed that endoscopic type and suture type were the influencing factors of problem events, and single lumen operation and inverted mirror suture were more likely to occur problem events than double lumen and positive mirror suture. The location of lesions was not the influencing factor of problem events, and the difference was not statistically significant (P > 0.05).Conclusion By analyzing the causes of human factors, wound location factors and device quality factors, the corresponding countermeasures are put forward, so as to reduce and avoid unnecessary problem events and improve the operation efficiency.