Mimics个体化三维重建联合径向超声支气管镜在肺外周结节诊断中的应用价值

Clinical value of individualized three-dimensional reconstruction based on Mimics software combined with ultrasound bronchoscope in diagnosis of peripheral pulmonary nodules

摘要:

目的 探讨Mimics软件三维重建虚拟支气管树联合径向超声检查在肺外周结节诊断中的应用价值。方法 选择2020年1月1日－2021年2月28日接受径向超声支气管镜（R-EBUS）检查的外周孤立性肺结节（SPN）患者23例，随机分为Mimics+R-EBUS组和R-EBUS组，R-EBUS组术前手绘导航定位肺结节，Mimics+R-EBUS组在术前利用Mimics软件对肺结节和支气管树进行三维重建以及检查路径设计，实现对肺结节定位。两组患者术中均行快速现场评价（ROSE）以对活检标本质量进行评估。比较两组患者手术时间、并发症发生率和诊断率的差异。结果 Mimics+R-EBUS组定位时间和操作时间短于R-EBUS组；两组患者并发症发生率和诊断率比较，差异无统计学意义（P > 0.05）。结论 Mimics个体化三维重建虚拟支气管树可为R-EBUS检查提供良好的定位与导航，缩短手术时间，具有临床应用价值。

Abstract:

Objective To explore the application value of Mimics software three-dimensional reconstruction of virtual bronchial tree combined with radial ultrasound in diagnosis of peripheral lung nodules.Methods From January 1, 2020 to February 28, 2021, 23 patients with peripheral solitary pulmonary nodule (SPN) underwent radial-endobronchial ultrasound (R-EBUS) examination, randomized divided into Mimics + R-EBUS group and R-EBUS group. In the R-EBUS group, the nodules were located by hand-painted navigation before operation, the Mimics + R-EBUS group used Mimics software to perform three-dimensional reconstruction of lung nodules and bronchial trees and design inspection paths before surgery. In both groups, rapid on-site evaluation (ROSE) was performed to evaluate the quality of biopsy specimens. Finally, the differences in operation time, complication rate, and diagnosis rate between the two groups were compared.Results The positioning time and operation time of the Mimics+R-EBUS group was shorter than that of the R-EBUS group. There was no statistical difference in the incidence of complications and diagnosis rate between the two groups.Conclusion The personalized virtual bronchial tree based on Mimics three-dimensional reconstruction can provide good positioning and navigation for radial ultrasound bronchoscopy, shorten the operation time, and has clinical application value.