Abstract:Objective To investigate the safety and feasibility of primary closure after laparoscopic common bile duct exploration (LCBDE) for patients with choledocholithiasis complicated with acute cholangitis.Methods The clinical data of 108 patients who underwent primary closure after LCBDE from January 2015 to August 2020 were retrospectively analyzed. Patients were divided into two groups according to the presence or absence of acute cholangitis before operation. The operative time, intraoperative blood loss, postoperative extubation time, postoperative hospital stay and postoperative complications were compared and analyzed between the two groups.Results Laparoscopic surgery was successfully completed in both groups, and no patient was transferred to laparotomy. Compared with the group without cholangitis, the intraoperative blood loss was more than that in the group with cholangitis (P = 0.010), and the difference was statistically significant. There was no significant difference between the two groups in operative time, postoperative extubation time, postoperative hospitalization time (P > 0.05). There was also no significant difference in the incidence of postoperative complications between the two groups (P > 0.05).Conclusion Under the premise of following the relevant surgical indications, primary closure after LCBDE is safe and feasible in the treatment of patients with choledocholithiasis complicated with acute cholangitis.