Abstract:Objective To explore the diagnostic value of double balloon enteroscopy (DBE) combined with computed tomography enterography (CTE) in intestinal diseases.Methods Sixty-five patients with intestinal diseases of unknown etiology were included, and CTE and DBE examinations were performed to analyze the detection rate of the etiology by DBE, CTE and their combined examinations.Results In patients with unexplained gastrointestinal bleeding, wasting and abdominal pain, DBE was superior to CTE (P < 0.01). The combined examination was better than the single examination of CTE or DBE (P < 0.01). For patients with unexplained abdominal distension, the detection rate of combined examination was the same as that of single examination of DBE, both of which were better than that of CTE (P < 0.01). ROC curve indicated that the combined detection rate was higher.Conclusion For patients with unexplained gastrointestinal bleeding, DBE or a combination of the two can be preferred. For patients with suspected intestinal space occupation or stenosis, CTE in small intestine is preferred. Combined application of DBE and CTE can complement each other according to the patient's situation, which can greatly improve the diagnosis rate of intestinal diseases.