Abstract:Objective To evaluate the changes and safety of various indicators of patient with tympanic membrane perforation during and after otoendoscopic and microscopic tympanoplasty.Methods 74 patients with tympanic membrane perforation from January 2016 to June 2018 were divided into two groups, otoendoscopy group (n = 37) was treated with tympanoplasty under ear endoscope, microscopic group (n = 37) was treated with tympanoplasty under microscopy. Relevant surgical indicators, tympanic membrane healing, hearing improvement and complications were observed.Results Compared with the microscopic group, the completion rate of otoendoscopy group was significantly higher in 40 ~ 50 min and 50 ~ 60 min, the average operation time was significantly shorter, the average bleeding volume was significantly less, and the hospital stay was significantly shorter after operation (χ2 = 5.05, 22.42, t = 7.88, 17.21, 9.37, P < 0.05); VAS score at 24 h after operation in otoendoscopy group was significantly lower than that in microscopy group (t = 25.00, P < 0.05); There was no significant difference in the healing rate of tympanic membrane between the two groups at 1, 6 and 12 months after operation (χ2 = 0.21, 0.16, 0.13, P > 0.05); The average air conduction hearing threshold and air-bone conduction difference of the two groups after operation were significantly lower than those before operation (P < 0.05), but there was no significant difference between the two groups (P > 0.05); The total incidence of postoperative complications in otoendoscopy group was 2.70%, which was significantly lower than that in microscopy group (16.22%) (χ2 = 3.94, P < 0.05).Conclusion Myringoplasty under microscopy and otoendoscopy is used to treat tympanic membrane perforation caused by otitis media, compare with otoendoscopic tympanoplasty, tympanoplasty is more time-saving, less bleeding, less pain, and can significantly reduce postoperative complications.