Abstract:Objective To compare the clinical efficacy of endoscopic thyroid with chest-breast approach and traditional surgery in the treatment of benign thyroid disease.Methods 106 patients underwent thyroid surgery from July 2014 to December 2019, divided into endoscopic group (n = 53) and traditional group (n = 53). The operation time, intraoperative blood loss, postoperative drainage volume, drainage time, postoperative hospital stay, postoperative pain medication requirements, and the incidence of complications between the two groups were compared.Results There were no statistically significant differences in the intraoperative blood loss, postoperative hospital stay, postoperative pain medication requirements, and incidence of complications (P > 0.05). The operation time and drainage time of endoscopic group were longer than those in traditional group, postoperative drainage volume of endoscopic group was more than that of traditional group, and the difference were statistically significant (P < 0.05).Conclusion Endoscopic thyroid with chest-breast approach is not significantly different from traditional surgery in the safety and feasibility of treating benign thyroid disease; However, the operation time and drainage time is longer and the drainage volume is more than traditional surgery.