Abstract:Objective To explore the efficacy and safety of day surgery of percutaneous nephrolithotomy (PCNL) under local anesthesia.Methods From January 2019 to December 2019, 65 patients with upper urinary tract calculi qualified for PCNL operation were selected. 30 patients in the observation group underwent PCNL day sugery under local anesthesia; 35 patients in the control group, PCNL was performed under epidural anesthesia. The patients were 18~60 years old. The maximum diameter of calculi ≤ 3.0 cm. There was no urinary tract infection and other complications before operation. Hydronephrosis was less than moderate (pelvis separation ≤ 3.0 cm). There was no significant difference in age, gender, side, stone diameter and stone location between the two groups (P > 0.05). The operation time (including anesthesia time), hospitalization time, postoperative hemoglobin reduction, postoperative pain score, hospitalization cost, incidence of complications and stone-free rate one month after operation were observed.Results All of the operations were successfully. The operation time, hospitalization time and hospitalization cost in observation group were significantly lower than those in the control group (P < 0.05). There was no significant difference in hemoglobin reduction, pain score and stone -free rate between the two groups (P > 0.05); There were 2 cases of fever (BT < 38℃) after operation in observation group, which recovered spontaneously without special treatment. There were 2 cases of fever after operation in control group, 1 case of incision hemorrhage when extubated fistula, no further bleeding after local compression. There was no significant difference in the incidence of complications between the two groups (P > 0.05).Conclusion For some selective upper urinary tract stones, PCNL day surgery under local anesthesia can shorten the hospitalization time, reduce the cost of hospitalization, and do not increase the risk of surgery, and can achieve the purpose of rapid recovery. But its indications and operation process need to be further explored and standardized.