内镜下结直肠息肉切除术后迟发性出血危险因素的Meta分析
作者:
作者单位:

浙江中医药大学附属第一医院 消化内科,浙江 杭州 310006

作者简介:

通讯作者:

孟立娜,E-mail:mln6713@163.com

基金项目:

国家自然科学基金(No:81373877)


Risk factors for delayed colonic post-polypectomy bleeding: a Meta-analysis
Author:
Affiliation:

Department of Gastroenterology, the First Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Hangzhou, Zhejiang 310006, China

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
    摘要:

    目的 分析结直肠息肉切除术后迟发性出血(DPPB)的主要危险因素。方法 通过计算机检索CNKI、万方数据库、维普数据库、PubMed、Embase和Cochrane Library有关结直肠DPPB的文献,根据Cochrane系统评价手册对筛选的文献进行质量评价,选用RevMan 5.3.5软件对筛选的文献进行Meta分析。结果 结直肠DPPB发生率男性高于女性(O = 1.39,95%CI:1.12~1.72,P = 0.002);高血压和糖尿病患者发生结直肠DPPB的风险增高(O = 1.79,95%CI:1.07~3.00,P = 0.030;O = 0.53,95%CI:0.38~0.75,P = 0.000);直径大于1 cm的息肉较小于1 cm的息肉更易发生结直肠DPPB(O = 0.35,95%CI:0.21~0.59,P = 0.000);有蒂息肉发生结直肠DPPB比无蒂息肉风险更高(O = 2.37,95%CI:1.12~5.00,P = 0.020);与炎性或增生性息肉相比,腺瘤性息肉患者DPPB明显升高(O = 3.02,95%CI:1.81~5.03,P = 0.000)。结论 男性、高血压、糖尿病、息肉直径、息肉形态和病理类型均为影响结直肠DPPB的主要危险因素。

    Abstract:

    Objective To analyze the risk factors of delayed postpolypectomy bleeding (DPPB).Methods CNKI, Wanfang database, VIP database, PubMed, Embase and Cochrane Library were searched for studies that investigated the risk factors for DPPB. The selected literature was evaluated according to the Cochrane Systematic Review Manual. The selected articles were analyzed by RevMan 5.3.5.Results Colorectal DPPB was higher in males than that in females (O = 1.39, 95%CI: 1.12~1.72, P = 0.002); Patients with hypertension and diabetes were incresed risk of colorectal DPPB (O = 1.79, 95%CI: 1.07~3.00, P = 0.030; O = 0.53,95%CI: 0.38~0.75,P = 0.000); The polyps' diameter larger than 1 cm are more likely to have colorectal DPPB (O = 0.35, 95%CI: 0.21~0.59, P = 0.000); The risk of colorectal DPPB in pedicled polyps was higher than in sessile polyps (O = 2.37, 95%CI: 1.12~5.00, P = 0.020); Patients with adenomatous polyps were more likely to have colorectal DPPB (O = 3.02, 95%CI: 1.81~5.03, P = 0.000).Conclusion Meta-analysis showed that male, hypertension, diabetes, polyps' diameter, polyps' morphology and pathological type were risk factors for colorectal DPPB.

    表 2 Table 2
    表 1 Table 1
    参考文献
    相似文献
    引证文献
引用本文
分享
文章指标
  • 点击次数:
  • 下载次数:
历史
  • 收稿日期:2020-05-28
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2021-01-08