脑电双频指数监测下右美托咪定在无痛支气管镜检查中的临床应用*

Clinical application of Dexmedetomidine in painless bronchoscopy with bispectral index monitoring*

摘要:

摘要：目的??探讨脑电双频指数（BIS）监测下右美托咪定联合丙泊酚和舒芬太尼在无痛支气管镜检查中的临床效果。方法 选取2019年4月－2019年7月接受气管镜检查的患者70例，随机分为观察组（右美托咪定组35例）和对照组（丙泊酚组35例）。观察两组患者的术中血流动力学、镇静评分、BIS值、药物使用量、手术时间、术后不良反应、患者及医师满意度，并进行对比分析。结果 观察组术中血流动力学较对照组平稳，T5时点平均动脉压（MAP）、T4～T8脉搏血氧饱和度（SpO2）较对照组高，而术中心率（HR）、BIS值较对照组低；两组改良警觉/镇静评分（MOAA/S）比较，在T2～T7时间点组间差异无统计学意义（P?>?0.05）；观察组麻醉时间、苏醒时间和出室时间较对照组长，两组比较，差异均有统计学意义（P?

Abstract:

Abstract: Objective?To explore the clinical effect of Dexmedetomidine combined with Propofol and Sufentanil in painless bronchoscopy with bispectral index monitoring.?Methods?There were 70 patients included in the study and randomly divided into two groups from April 2019 to July 2019: the observation group (35 cases of Dexmedetomidine group) and the control group (35 cases of Propofol group). The intraoperative hemodynamics, sedation score, BIS value, drug consumption, operation time, postoperative adverse reactions, satisfaction of patient and physician were observed and compared between the two groups.?Results?Compared with the control group, in the observation group, the intraoperative hemodynamics were more stable, the mean arterial blood pressure at T5 and the oxygen saturation of blood at T4 ~ T8 were higher, heart rate and BIS value were lower during the operation. There was no significant difference in the MOAA/S sedation score between the two groups at T2 ~ T7 (P?>?0.05). In terms of operation time, the anesthesia time, recovery time and out of the room time of the observation group were longer, and the difference was statistically significant (P?